How To Disinfect a Used Mattress: Step‑by‑Step FAQ Guide
If you’ve just brought home a secondhand bed or are reusing an older one, you may be asking “How To Disinfect a Used Mattress” safely and effectively. This guide walks through what “disinfecting” really means for a mattress, how to do it at home, and when a mattress may not be worth trying to save.
What does it mean to disinfect a used mattress?
When people ask how to disinfect a used mattress, they usually want to:
- Reduce germs and surface contaminants
- Remove odors and visible dirt
- Feel more comfortable sleeping on a mattress that someone else used
At home, you can clean deeply and sanitize a mattress, but it is difficult to achieve the same level of disinfection you might get from professional equipment. The goal is to significantly improve cleanliness, not to promise a completely sterile surface.
What should I check before disinfecting a used mattress?
Before you start, inspect the mattress carefully. In some cases, cleaning may not be enough.
Look for:
- Visible mold or heavy staining
- Strong, persistent odors that don’t fade in fresh air
- Evidence of pests, such as tiny dark spots, shed skins, or live insects
- Major structural damage, like sagging or broken springs
If you see clear signs of pests or widespread mold, many people choose not to keep the mattress, because those issues can be hard to fully resolve at home.
Step‑by‑step: How To Disinfect a Used Mattress at home
1. Strip and vacuum thoroughly
- Remove all bedding, protectors, and covers.
- Use a vacuum with an upholstery attachment.
- Vacuum all surfaces, including:
- Top and sides
- Seams and tufts
- Any creases or labels
This step helps remove loose dirt, skin flakes, hair, and dust, which can hold odors and grime.
2. Spot clean stains
Mix a mild cleaning solution, such as:
- A small amount of gentle liquid soap with water, or
- A small amount of diluted, non‑bleach upholstery cleaner as directed on its label
Lightly dampen a clean cloth (do not soak it) and:
- Blot, don’t scrub, starting from the outside of the stain and moving inward.
- Use a second cloth dampened with plain water to remove soapy residue.
- Blot with a dry towel to remove excess moisture.
Mattresses should never be saturated with water. Too much moisture can be hard to dry and may encourage odors or mold.
3. Deodorize the surface
To help with mild odors:
- Sprinkle a light, even layer of baking soda over the entire sleeping surface.
- Let it sit for several hours, or longer if possible.
- Vacuum thoroughly again to remove all residue.
Baking soda does not disinfect, but it can help absorb and reduce common mattress smells.
4. Use a suitable disinfecting approach
There is no single method that fits every mattress, but common at‑home options include:
Disinfectant sprays labeled safe for fabrics:
- Check that the product states it is suitable for soft surfaces.
- Lightly mist (do not soak) the mattress surface.
- Follow the contact time on the label and let it dry fully.
Steam (with caution):
- Some people use a household steam cleaner on mattresses.
- Use the lowest effective setting and keep the steamer moving to avoid over‑wetting.
- Not all mattress materials respond well to heat and moisture, so it’s wise to test a small area first.
The aim is to reduce surface germs while keeping the mattress as dry and intact as possible.
5. Air out and fully dry the mattress
After cleaning and treating:
- Place the mattress in a well‑ventilated area.
- If possible, position it near an open window or use a fan to improve air circulation.
- Allow several hours or more for the mattress to dry completely before putting on sheets.
A fully dry mattress is less likely to retain odors or moisture.
Is it safe to disinfect a used mattress yourself?
Many people do disinfect and reuse used mattresses at home, especially when the mattress:
- Comes from a known, trusted source
- Has no signs of pests or mold
- Is in good structural condition
Home cleaning and sanitizing can greatly improve how clean and fresh the mattress feels. If you have specific health concerns or sensitivities, consider your comfort level with using a previously owned mattress, even after thorough cleaning.
How can I keep a disinfected used mattress cleaner for longer?
Once you have followed the steps for how to disinfect a used mattress, ongoing care can help keep it fresher:
- Use a washable mattress protector to create a barrier against spills, sweat, and skin flakes.
- Wash bedding regularly, including sheets and pillowcases.
- Air out the mattress occasionally by removing bedding and letting it breathe.
- Vacuum the surface from time to time to remove dust and debris.
These simple habits can extend the time between deeper cleanings.
When is a used mattress not worth disinfecting?
It may be difficult or impractical to fully clean a mattress that:
- Has heavy, deep stains across large areas
- Shows visible mold growth or strong musty smells
- Has clear signs of bed bugs or other pests
- Is already very old, sagging, or uncomfortable
In those situations, cleaning efforts may not provide the level of reassurance or comfort you’re looking for.
✅ Quick Mattress Takeaways
Key points consumers should understand about How To Disinfect a Used Mattress
- Start with inspection: Check for pests, mold, strong odors, and damage before deciding to keep a used mattress.
- Clean in layers: Vacuum, spot clean, deodorize, then use a suitable disinfecting method such as a fabric‑safe spray or cautious steam.
- Avoid soaking: Too much liquid can be hard to dry and may cause new issues.
- Dry thoroughly: Good ventilation and enough drying time are essential after any cleaning or disinfecting step.
- Use protection going forward: A mattress protector and regular maintenance help keep a disinfected used mattress feeling fresher longer.
With a careful process and realistic expectations, how to disinfect a used mattress becomes a manageable task that can help you feel more comfortable resting on a previously owned bed.

